[HTML][HTML] Double plant homeodomain (PHD) finger proteins DPF3a and-3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF …
A Ishizaka, T Mizutani, K Kobayashi, T Tando… - Journal of Biological …, 2012 - ASBMB
We have previously shown that DPF2 (requiem/REQ) functions as a linker protein between
the SWI/SNF complex and RelB/p52 NF-κB heterodimer and plays important roles in NF-κB
transactivation via its noncanonical pathway. Using sensitive 293FT reporter cell clones that
had integrated a SWI/SNF-dependent NF-κB reporter gene, we find in this study that the
overexpression of DPF1, DPF2, DPF3a, DPF3b, and PHF10 significantly potentiates the
transactivating activity of typical NF-κB dimers. Knockdown analysis using 293FT reporter …
the SWI/SNF complex and RelB/p52 NF-κB heterodimer and plays important roles in NF-κB
transactivation via its noncanonical pathway. Using sensitive 293FT reporter cell clones that
had integrated a SWI/SNF-dependent NF-κB reporter gene, we find in this study that the
overexpression of DPF1, DPF2, DPF3a, DPF3b, and PHF10 significantly potentiates the
transactivating activity of typical NF-κB dimers. Knockdown analysis using 293FT reporter …