Importance Although clonal hematopoiesis (CH) is well described in aging healthy
populations, few studies have addressed the practical clinical implications of these
alterations in solid-tumor sequencing. Objective To identify and quantify CH-related
mutations in patients with solid tumors using matched tumor-blood sequencing, and to
establish the proportion that would be misattributed to the tumor based on tumor-only
sequencing (unmatched analysis). Design, Setting, and Participants Retrospective analysis …