[HTML][HTML] Complete Genome Sequence, Genome Stability and Phylogeny of the Vaccine Strain Mycobacterium bovis BCG SL222 Sofia
Mycobacterium bovis bacillus Calmette–Guérin (BCG) is the only live attenuated vaccine
available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in
1921. The BCG vaccine strains used worldwide represent a family of daughter sub-strains
with distinct genotypic characteristics. BCG SL222 Sofia is a seed lot sub-strain descending
from the Russian BCG-I (seed lot 374a) strain and has been used for vaccine production in
Bulgaria since 1972. Here, we report the assembled circular genome sequence of …
available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in
1921. The BCG vaccine strains used worldwide represent a family of daughter sub-strains
with distinct genotypic characteristics. BCG SL222 Sofia is a seed lot sub-strain descending
from the Russian BCG-I (seed lot 374a) strain and has been used for vaccine production in
Bulgaria since 1972. Here, we report the assembled circular genome sequence of …
[PDF][PDF] Complete Genome Sequence, Genome Stability and Phylogeny of the Vaccine Strain Mycobacterium bovis BCG SL222 Sofia. Vaccines 2021, 9, 237
Mycobacterium bovis bacillus Calmette–Guérin (BCG) is the only live attenuated vaccine
available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in
1921. The BCG vaccine strains used worldwide represent a family of daughter sub-strains
with distinct genotypic characteristics. BCG SL222 Sofia is a seed lot sub-strain descending
from the Russian BCG-I (seed lot 374a) strain and has been used for vaccine production in
Bulgaria since 1972. Here,
available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in
1921. The BCG vaccine strains used worldwide represent a family of daughter sub-strains
with distinct genotypic characteristics. BCG SL222 Sofia is a seed lot sub-strain descending
from the Russian BCG-I (seed lot 374a) strain and has been used for vaccine production in
Bulgaria since 1972. Here,