[HTML][HTML] Association between anticoagulation and survival in interstitial lung disease: an analysis of the pulmonary fibrosis foundation patient registry
CS King, E Freiheit, AW Brown, OA Shlobin, S Aryal… - Chest, 2021 - Elsevier
Background Aberrations in the coagulation system have been implicated in the
pathogenesis of interstitial lung disease (ILD). Anticoagulants have been proposed as a
potential therapy in ILD; however, a randomized controlled trial examining warfarin as a
treatment for IPF was terminated early due to increased death rates. This has led some to
speculate that warfarin specifically may be harmful in ILD, and use of direct oral
anticoagulants (DOACs) could result in superior outcomes. Research Question The goal of …
pathogenesis of interstitial lung disease (ILD). Anticoagulants have been proposed as a
potential therapy in ILD; however, a randomized controlled trial examining warfarin as a
treatment for IPF was terminated early due to increased death rates. This has led some to
speculate that warfarin specifically may be harmful in ILD, and use of direct oral
anticoagulants (DOACs) could result in superior outcomes. Research Question The goal of …
