[PDF][PDF] NF-κB: the inducible factors of HIV-1 transcription and their inhibitors
Y Mingyan, L Xinyong, E De Clercq - Mini reviews in medicinal …, 2009 - researchgate.net
Y Mingyan, L Xinyong, E De Clercq
Mini reviews in medicinal chemistry, 2009•researchgate.netNF-kappaB (NF-κB), the transcription factors of HIV-1, play an important role in triggering
HIV transcription. The inhibition of NF-κB activation and their signaling pathway offers a
potential anti-HIV therapy strategy. This review reports the mode of action of NF-κB in
triggering HIV-1 transcription and the status of the inhibitors.
HIV transcription. The inhibition of NF-κB activation and their signaling pathway offers a
potential anti-HIV therapy strategy. This review reports the mode of action of NF-κB in
triggering HIV-1 transcription and the status of the inhibitors.
Abstract
NF-kappaB (NF-κB), the transcription factors of HIV-1, play an important role in triggering HIV transcription. The inhibition of NF-κB activation and their signaling pathway offers a potential anti-HIV therapy strategy. This review reports the mode of action of NF-κB in triggering HIV-1 transcription and the status of the inhibitors.
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