Microglia in the developing brain: a potential target with lifetime effects

GJ Harry, AD Kraft - Neurotoxicology, 2012 - Elsevier
Microglia are a heterogenous group of monocyte-derived cells serving multiple roles within
the brain, many of which are associated with immune and macrophage like properties.
These cells are known to serve a critical role during brain injury and to maintain
homeostasis; yet, their defined roles during development have yet to be elucidated.
Microglial actions appear to influence events associated with neuronal proliferation and
differentiation during development, as well as, contribute to processes associated with the …