[HTML][HTML] Eradication of human immunodeficiency virus-1 reservoir in the brain microglia
Human immunodeficiency virus-1 (HIV) reservoirs in the human brain: Antiretroviral therapy
(ART) effectively decreases active HIV replication to undetectable levels. Therefore, it greatly
improves the quality of life for people living with HIV (PLWH). However, except for a few
exceptional cases after stem-cell transplantation from CCR5Δ32 mutation donors, such as in
Berlin and London patients, there is no cure for HIV, due to the latent HIV reservoirs
harbored in the long-lived HIV permissive cells. HIV quickly rebounds upon the disruption of …
(ART) effectively decreases active HIV replication to undetectable levels. Therefore, it greatly
improves the quality of life for people living with HIV (PLWH). However, except for a few
exceptional cases after stem-cell transplantation from CCR5Δ32 mutation donors, such as in
Berlin and London patients, there is no cure for HIV, due to the latent HIV reservoirs
harbored in the long-lived HIV permissive cells. HIV quickly rebounds upon the disruption of …