The ADscopal effect? Control of partially irradiated versus completely irradiated tumors on a prospective trial of pembrolizumab and SBRT per NRG-BR001
JM Lemons, JJ Luke, L Janisch, R Hseu… - International Journal of …, 2017 - redjournal.org
Results A total of 96 lesions were radiated including 25 peripheral lung, 18 central lung, 8
mediastinal/cervical, 15 liver, 21 abdominal-pelvic, 5 osseous, and 4 spinal lesions. Median
follow-up was 14 wks (range 4–52 wks). Fourteen lesions were partially irradiated using a
SUCITV (partial group) and 82 lesions were completely irradiated using the original GTV
(complete group). Mean GTV size was significantly larger in the partial group (177 cc vs 11
cc, P< 0.001). In the partial group, the mean volume of GTV excluded from the target SUCITV …
mediastinal/cervical, 15 liver, 21 abdominal-pelvic, 5 osseous, and 4 spinal lesions. Median
follow-up was 14 wks (range 4–52 wks). Fourteen lesions were partially irradiated using a
SUCITV (partial group) and 82 lesions were completely irradiated using the original GTV
(complete group). Mean GTV size was significantly larger in the partial group (177 cc vs 11
cc, P< 0.001). In the partial group, the mean volume of GTV excluded from the target SUCITV …