[HTML][HTML] The hyperglycemia stranglehold stifles cutaneous epithelial‒mesenchymal plasticity and functional wound closure
Iterative cycles of epithelial‒mesenchymal transition (EMT) and mesenchymal-to-epithelial
transition (MET) are responsible for epithelial plasticity necessary to achieve functional
wound closure. Restoration of the barrier function of the repaired skin is a hallmark of
functional wound closure. Both EMT and MET are subject to control by glycemic status. A
new article by Tan et al (2020) supports the notion that hyperglycemia blunts epithelial
plasticity.
transition (MET) are responsible for epithelial plasticity necessary to achieve functional
wound closure. Restoration of the barrier function of the repaired skin is a hallmark of
functional wound closure. Both EMT and MET are subject to control by glycemic status. A
new article by Tan et al (2020) supports the notion that hyperglycemia blunts epithelial
plasticity.
Iterative cycles of epithelial‒mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) are responsible for epithelial plasticity necessary to achieve functional wound closure. Restoration of the barrier function of the repaired skin is a hallmark of functional wound closure. Both EMT and MET are subject to control by glycemic status. A new article by Tan et al (2020) supports the notion that hyperglycemia blunts epithelial plasticity.
Elsevier
