Autophagy regulates lipid production and contributes to the sebosuppressive effect of retinoic acid in human SZ95 sebocytes
SH Seo, JY Jung, K Park, AM Hossini… - Journal of …, 2020 - Elsevier
Background Autophagy is a catabolic process for eliminating damaged organelles or
proteins to maintain cellular homeostasis. Recently, lipids have been demonstrated to be
targets for autophagosomal degradation. Therefore, autophagy might be involved in
sebaceous gland homeostasis, however, relevant data are lacking. Objectives We
investigated the role of autophagy in sebaceous lipogenesis and its regulatory mechanisms
in human SZ95 sebocytes. We also examined the possible role of autophagy in 13-cis …
proteins to maintain cellular homeostasis. Recently, lipids have been demonstrated to be
targets for autophagosomal degradation. Therefore, autophagy might be involved in
sebaceous gland homeostasis, however, relevant data are lacking. Objectives We
investigated the role of autophagy in sebaceous lipogenesis and its regulatory mechanisms
in human SZ95 sebocytes. We also examined the possible role of autophagy in 13-cis …