Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA …
Y Saito, M Yokoyama, H Origasa, M Matsuzaki… - Atherosclerosis, 2008 - Elsevier
BACKGROUND: Japan EPA Lipid Intervention Study (JELIS) was a large-scale clinical trial
examining the effects of eicosapentaenoic acid (EPA) on coronary artery disease (CAD) in
hypercholesterolemic patients. Herein, we focused on risk factors other than low-density
lipoprotein cholesterol (LDL-C) to investigate the effects of EPA on CAD among JELIS
primary prevention cases. METHODS: Hypercholesterolemic patients on statin therapy but
without evidence of CAD (n= 14,981) were randomly assigned to an EPA group (n= 7503) or …
examining the effects of eicosapentaenoic acid (EPA) on coronary artery disease (CAD) in
hypercholesterolemic patients. Herein, we focused on risk factors other than low-density
lipoprotein cholesterol (LDL-C) to investigate the effects of EPA on CAD among JELIS
primary prevention cases. METHODS: Hypercholesterolemic patients on statin therapy but
without evidence of CAD (n= 14,981) were randomly assigned to an EPA group (n= 7503) or …
