[HTML][HTML] Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease: Thematic review series: New lipid and lipoprotein targets for the …
G Porez, J Prawitt, B Gross, B Staels - Journal of lipid research, 2012 - ASBMB
Dyslipidemia is an important risk factor for cardiovascular disease (CVD) and
atherosclerosis. When dyslipidemia coincides with other metabolic disorders such as
obesity, hypertension, and glucose intolerance, defined as the metabolic syndrome (MS),
individuals present an elevated risk to develop type 2 diabetes (T2D) as well as CVD.
Because the MS epidemic represents a growing public health problem worldwide, the
development of therapies remains a major challenge. Alterations of bile acid pool regulation …
atherosclerosis. When dyslipidemia coincides with other metabolic disorders such as
obesity, hypertension, and glucose intolerance, defined as the metabolic syndrome (MS),
individuals present an elevated risk to develop type 2 diabetes (T2D) as well as CVD.
Because the MS epidemic represents a growing public health problem worldwide, the
development of therapies remains a major challenge. Alterations of bile acid pool regulation …