Progenitor-derived oligodendrocyte culture system from human fetal brain

MCG Monaco, D Maric, A Bandeian… - JoVE (Journal of …, 2012 - jove.com
Differentiation of human neural progenitors into neuronal and glial cell types offers a model
to study and compare molecular regulation of neural cell lineage development. In vitro
expansion of neural progenitors from fetal CNS tissue has been well characterized. Despite
the identification and isolation of glial progenitors from adult human sub-cortical white matter
and development of various culture conditions to direct differentiation of fetal neural
progenitors into myelin producing oligodendrocytes, acquiring sufficient human …