[30] Sphingolipid hydrolyzing enzymes in the gastrointestinal tract

RD Duan - Methods in enzymology, 2000 - Elsevier
Publisher Summary In the intestinal tract, there are enzymes that hydrolyze both
endogenous and exogenous sphingolipids. The alkaline sphingomyelinases (SMase) of the
gut and human bile have been most studied, and a major part of this chapter discusses
these enzymes. It also discusses studies of ceramidase, glycosylceramidase, and the
digestion of dietary sphingolipids. In the intestinal tract, a distinct enzyme that hydrolyzes SM
was discovered in 1969 by Nilsson and named “alkaline SMase.” The alkaline SMase …