Plasma “factors” in recurrent nephrotic syndrome after kidney transplantation: causes or consequences of glomerular injury?
VJ Savin, M Sharma - American Journal of Kidney Diseases, 2009 - ajkd.org
The recurrence of nephrotic syndrome after kidney transplantation is a particularly vexing
problem. Steroid-resistant nephrotic syndrome with progression to renal failure occurs most
often in the setting of focal segmental glomerulosclerosis (FSGS), a pathological diagnosis
that is observed in an increasing number of patients who undergo renal biopsy. In patients
with FSGS and those with idiopathic nephrotic syndrome (INS) that progresses to renal
failure, recurrence of nephrotic syndrome and eventual loss of renal allograft function occurs …
problem. Steroid-resistant nephrotic syndrome with progression to renal failure occurs most
often in the setting of focal segmental glomerulosclerosis (FSGS), a pathological diagnosis
that is observed in an increasing number of patients who undergo renal biopsy. In patients
with FSGS and those with idiopathic nephrotic syndrome (INS) that progresses to renal
failure, recurrence of nephrotic syndrome and eventual loss of renal allograft function occurs …
