Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration

F Facchini, YDI Chen, CB Hollenbeck, GM Reaven - Jama, 1991 - jamanetwork.com
Objective.—To define the relationship, if any, between insulin-mediated glucose disposal
and serum uric acid. Design.—Cross-sectional study of healthy volunteers. Setting.—
General Clinical Research Center, Stanford (Calif) University Medical Center. Participants.—
Thirty-six presumably healthy individuals, nondiabetic, without a history of gout.
Measurements.—Obesity (overall and regional), plasma glucose and insulin responses to a
75-g oral glucose load, fasting uric acid concentrations, plasma triglyceride and high-density …