Regulatory T cells in transplantation

M Karim, AR Bushell, KJ Wood - Current Opinion in immunology, 2002 - Elsevier
M Karim, AR Bushell, KJ Wood
Current Opinion in immunology, 2002Elsevier
There has recently been an explosion of renewed interest in regulatory T cells, particularly
those within the CD4+ CD25+ population. It is becoming increasingly apparent that these
cells exist not only as naturally occurring cells that may contribute to the maintenance of self-
tolerance, but they also have the potential to prevent rejection of allografts in experimental
models. Such cells have now been identified in humans as well as in rodents.
There has recently been an explosion of renewed interest in regulatory T cells, particularly those within the CD4+CD25+ population. It is becoming increasingly apparent that these cells exist not only as naturally occurring cells that may contribute to the maintenance of self-tolerance, but they also have the potential to prevent rejection of allografts in experimental models. Such cells have now been identified in humans as well as in rodents.
Elsevier