Analysis of oxidized phosphatidylcholines as markers for oxidative stress, using multiple reaction monitoring with theoretically expanded data sets with reversed …

H Nakanishi, Y Iida, T Shimizu, R Taguchi - Journal of Chromatography B, 2009 - Elsevier
Recently, it was reported that oxidized phosphatidylcholine shows biological activities via
scavenger receptor CD36 or Toll-like receptor 4 (TLR4)-TRIF. Thus, the analysis of oxidized
phospholipids is essential in understanding these biological roles. Here, we report an
analytical method for oxidized phosphatidylcholines using multiple reaction monitoring
(MRM) with theoretically expanded data sets. This analytical method was performed by a
quadrupole linear ion trap mass spectrometer with ultra performance LC (UPLC). To …