Spermatogenesis that occurs in the seminiferous epithelium of adult mammalian testes is
associated with extensive junction restructuring at the Sertoli–Sertoli cell, Sertoli–germ cell,
and Sertoli–basement membrane interface. While this morphological phenomenon is known
and has been described in great details for decades, the biochemical and molecular
changes as well as the mechanisms/signaling pathways that define changes at the cell–cell
and cell–matrix interface remain largely unknown until recently. In this chapter, we …