Adrenomedullin is increased in the fetoplacental circulation in intrauterine growth restriction with abnormal umbilical artery waveforms

R Di Iorio, E Marinoni, C Letizia, D Gazzolo… - American journal of …, 2000 - Elsevier
OBJECTIVE:: To examine whether adrenomedullin, a novel vasoactive peptide produced by
the placenta, participates in the uteroplacental hemodynamic alterations in intrauterine
growth restriction, we studied the correlation between adrenomedullin levels and
fetoplacental blood flow. STUDY DESIGN:: Maternal and umbilical blood samples were
collected in pregnancies complicated by intrauterine growth restriction with abnormal
umbilical artery Doppler findings and in control pregnancies. Adrenomedullin levels were …